Even before the draft sequence of the human genome was completed, investors and companies were looking to the 'next big thing' — proteomics. Huge amounts of time and money were invested in proteomics-related ventures, and a crop of start-up companies emerged. Some firms set up large-scale proteomics factories running around the clock, with the aim of taking an inventory of the entire human proteome. A few years down the line, reality is setting in. How to turn proteomics data into products remains an open question and investors are becoming impatient.

See the list of the most frequently accessed papers from various sections of Bioinformatics in the last 5 years. This selection highlights the diversity and scope of the papers available. The information has been compiled using online usage statistics and the papers are listed within the following sections:

Top Review Papers
Top Editorial Papers
Top Papers